Inflammatory Disease Research Antibodies & Antigens

Inflammatory diseases are characterized by dysregulated immune responses that result in persistent tissue injury and impaired homeostasis. In autoimmune diseases the immune system targets self-antigens to cause excessive inflammation, for example in rheumatoid arthritis, inflammatory bowel disease, and psoriasis.

The proteins and antibodies in this category facilitate research into inflammatory pathways, cytokine networks, and potential therapeutic interventions. A central theme in this category is protein citrullination, recognized by anti-citrullinated protein antibodies (ACPAs) which represent the most specific serological markers of rheumatoid arthritis. AVS Bio offers a focused panel of monoclonal anti-citrullinated fibrinogen antibodies (in human and mouse formats) alongside antibodies to modified citrulline (clones C4 and C4S), supporting research into how citrullinated fibrinogen and related antigens affect the course of the disease.

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