Mouse anti-human PKM2

Mouse anti-human PKM2
Antibody against pyruvate kinase isoenzyme type M2 (PKM2 or M2-PK), one of the two isozymes encoded by the human PKM gene. The two isozymes M1 and M2 are alternative splicing products and differ in one of eleven exons. Pyruvate kinase is a critical enzyme in glycolysis as it dephosphorylates phosphoenolpyruvate (PEP) to pyruvate resulting in the net production ATP.  PKM2 is mainly found in differentiated tissues such as lung as well as in rapidly proliferating cells including tumor cells.