Noggin-Fc Fusion Protein Conditioned Medium
Noggin-Fc Fusion Protein Conditioned Medium
Noggin binds and inactivates members of the transforming growth factor-beta (TGF-beta) superfamily signaling proteins, such as bone morphogenetic protein-4 (BMP4). By diffusing through extracellular matrices more efficiently than members of the TGF-beta superfamily, this protein may have a principal role in creating morphogenic gradients. The protein appears to have pleiotropic effect, both early in development as well as in later stages. It was originally isolated from Xenopus based on its ability to restore normal dorsal-ventral body axis in embryos that had been artificially ventralized by UV treatment. The results of the mouse knockout of the ortholog suggest that it is involved in numerous developmental processes, such as neural tube fusion and joint formation.
New user exclusive offer: Receive a 10 ml trial package of Noggin-Fc fusion protein conditioned medium for € 85 (excluding tax and shipping). Send your request to products@avsbio.com (Offer limited to one per new user).
Production platform: This product has been produced in HEK293 cells using the rPEx® recombinant protein production platform.
